Lipid signalling
نویسندگان
چکیده
منابع مشابه
Lipid signalling
If you believe the fluid mosaic model of membrane structure, all the important jobs of the cell membrane, such as nutrient uptake, ion transport and transduction of hormonal signals, are attributable to membrane proteins rather than to the lipid bilayer in which they sit. But if all the membrane lipids do is to form a permeability barrier, you might expect them to have quite uniform structures....
متن کاملLipid phosphate phosphatases and lipid phosphate signalling.
Mammalian LPPs (lipid phosphate phosphatases) are integral membrane proteins that belong to a superfamily of lipid phosphatases/phosphotransferases. They have broad substrate specificity in vitro, dephosphorylating PA (phosphatidic acid), S1P (sphingosine 1-phosphate), LPA (lysophosphatidic acid) etc. Their physiological role may include the attenuation of S1P- and LPA-stimulated signalling by ...
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9 REVIEW OF THE LITERATURE 11 1. Cell membranes and cholesterol 11 1.1 Cellular membranes 11 1.1.1 Basic structure and components 11 1.1.2 Cholesterol-sphingolipid interaction 14 1.1.3 Distribution of cholesterol and other lipids in cell membranes 15 1.2 Cholesterol homeostasis in mammalian cells 16 1.2.1 Cholesterol biosynthesis, lipoprotein uptake and cholesterol efflux 16 1.2.2 Cholesterol e...
متن کاملLipid Signalling: Picking Out The PIPs
Many physiological targets have been suggested for polyphosphoinositol lipids, but two out of the three monophosphorylated PIPs appeared to be no more than metabolic precursors. Recent work has shown that they also have distinct binding proteins and functions.
متن کاملLearning the lipid language of plant signalling.
Plant cells respond to different biotic and abiotic stresses by producing various uncommon phospholipids that are believed to play key roles in cell signalling. We can predict how they work because animal and yeast proteins have been shown to have specific lipid-binding domains, which act as docking sites. When such proteins are recruited to the membrane locations where these phospholipids are ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1998
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(07)00546-5